Boron Analogs of Valine, Leucine, and Isoleucine: Synthesis of Amine-Alkyl(C-alkoxycarbonyl)boranes and Amine-Alkyl(N,N-diethylcarbamoyl)boranes
β Scribed by Sutton, Christopher H.; Baize, Mark W.; Todd, Lee J.
- Book ID
- 126881703
- Publisher
- American Chemical Society
- Year
- 1994
- Tongue
- English
- Weight
- 626 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0020-1669
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Acyclic amines **1** were obtained by a nucleophilic aromatic substitution (S~N~Ar) reaction and __N__βmethylation followed by silane reduction. The optical resolution of C(aryl)βN(amine) bond atropisomers of amines **1** is described. We found that chiral acyclic amine **1a** can be re
Using 1 -chloro-l-[~~N]nitrosocyclohexane, we have prepared five L-[a-'SN]arnino acids. The stereoselective electophillic hydroxyamination of (S)-acylbornane-l0,2-suftams, followed by ZnO/H+ reduction, and alkaline cleavage of the chiral auxiliary, gave the amino acids in 97.2-99.5 % e.e. By starti