Book review: Multivariate Models and Dependence Concepts. Harry Joe, Chapman & Hall, 1997. No. of pages: xiii+399. Price: £39. ISBN 412073 315
✍ Scribed by Steen Arne Andersson
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 50 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0277-6715
No coin nor oath required. For personal study only.
✦ Synopsis
which was effectively rebutted by a number of careful reviews which failed to find any defects in the design, execution or analysis of the trial. Marks tends to sympathize with those who criticized the choice of treatment regimens (such as the dosage of tolbutamide) or the methods of assessment of response. These criticisms may be valid, but they do not explain the excess mortality from tolbutamide, and it is difficult to see why regulatory action was so long delayed. Marks is right to see in this trial an illustration of the social and political context in which trials take place, and one wonders whether there is more to be learnt from background documents not yet in the public domain.
This book is very thoroughly researched. The reader should be warned, though, that a high proportion of the page area is taken up by footnotes, which contain all the references (many of which are to unpublished documents) and much important commentary. This is fine for a careful perusal of sources for a particular issue under discussion, but makes for a rather unsettling session for anyone wanting to read continuously through several chapters.