Bone turnover markers in serum and urine as diagnostic, prognostic and monitoring biomarkers of bone metastasis
β Scribed by Jung, Klaus; Lein, Michael
- Book ID
- 126852289
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 549 KB
- Volume
- 1846
- Category
- Article
- ISSN
- 0304-419X
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## Abstract Our aim was to assess the diagnostic accuracy of bone markers in serum of patients with prostate cancer (PCa) for early detection of bone metastases and their usefulness as predictors of PCaβcaused mortality. In sera of 117 PCa patients (pN0M0, __n__ = 39; pN1M0, __n__ = 34; M1, __n__ =
## Background: Although clinical investigations of bone turnover markers in prostate cancer patients have been conducted, the relationships of pretreatment levels of the markers to the prognosis of patients with bone metastasis has not been fully examined. ## Methods: The serum levels of carboxy-