Bone regeneration by transforming growth factor β1 released from a biodegradable hydrogel
✍ Scribed by Masaya Yamamoto; Yasuhiko Tabata; Liu Hong; Susumu Miyamoto; Nobuo Hashimoto; Yoshito Ikada
- Book ID
- 114163823
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 467 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0168-3659
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Recombinant human transforming growth factor 1 (TGF-1) was incorporated into biodegradable microparticles of blends of poly(DL-lactic-co-glycolic acid) (PLGA) and poly(ethylene glycol) (PEG) at 6 ng/1 mg microparticles. Fluorescein isothiocynate labeled bovine serum albumin (FITC-BSA) was coencaps
## Abstract Collagen/chitosan composite microgranules were fabricated as bone substitutes for the purpose of obtaining high bone‐forming efficacy. The microgranules have the flexibility to fill various types of defect sites with closer packing. The interconnected pores formed spaces between the mic