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Bone morphogenic protein 2 induces Runx2 and osteopontin expression in human aortic valve interstitial cells: Role of Smad1 and extracellular signal-regulated kinase 1/2

✍ Scribed by Xiaoping Yang; Xianzhong Meng; Xin Su; David C. Mauchley; Lihua Ao; Joseph C. Cleveland Jr.; David A. Fullerton


Book ID
113763381
Publisher
CTSNet
Year
2009
Tongue
English
Weight
650 KB
Volume
138
Category
Article
ISSN
1097-685X

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✍ Ya-Ling Hsu; Hsin-Lin Liang; Chih-Hsing Hung; Po-Lin Kuo πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 309 KB

## Abstract Syringetin (3,5,7,4′‐tetrahydroxy‐3β€²,5β€²dimethoxyflavone), a flavonoid derivative, is present in grape and wine. By means of alkaline phosphatase (ALP) activity, osteocalcin, and type I collagen ELISA, we have shown that syringetin exhibits a significant induction of differentiation in M