Bone morphogenetic proteins -2, -4, -6, -7 and their receptors are expressed in normal human kidney and renal cell carcinoma
โ Scribed by D. Markic; T. Celic; J. Spanjol; A. Grskovic; Z. Fuckar; D. Bobinac
- Book ID
- 116323152
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 55 KB
- Volume
- 47
- Category
- Article
- ISSN
- 8756-3282
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## Abstract ## Objective Bone morphogenetic protein (BMP) and transforming growth factor ฮฒ (TGFฮฒ) are potent anabolic factors in adult articular chondrocytes. In this study, we investigated whether intracellular inhibitors of BMP and TGFฮฒ signaling, inhibitory Smad6 (IโSmad6) and IโSmad7, are expr