Bone morphogenetic protein-7 (BMP-7) is downregulated in prostate cancer
✍ Scribed by Cyrill A Rentsch; Ruth Schwaninger; Antoinette Wetterwald; Regula Markwalder; Irena Klima; Franziska Geissbühler; Gabri van der Pluijm; Clemens W.G.M Löwik; Marco G Cecchini; Urs E Studer; George N Thalmann
- Book ID
- 118645084
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 100 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1569-9056
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We identified a__Xenopus__ gene closely related to mammalian bone morphogenetic protein (BMP)‐7 (also termed osteogenic protein‐1 or OP‐1). It resembles the mammalian gene in primary structure and expression pattern much more closely than does a previously described __Xenopus__ homologue, originally
## Abstract Bone morphogenetic proteins (BMP) make up a family of extracellular signaling molecules that play a critical role in vertebrate development and both inhibit and stimulate growth in cancer cells. __BMP7__ was recently identified in our genomewide copy number and expression survey as bein