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Bone morphogenetic protein-3 is a negative regulator of bone density

✍ Scribed by Lyons, Karen M.; Daluiski, Aaron; Engstrand, Thomas; Bahamonde, Matthew E.; Gamer, Laura W.; Agius, Eric; Stevenson, Sharon L.; Cox, Karen; Rosen, Vicki

Book ID
109829810
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
596 KB
Volume
27
Category
Article
ISSN
1061-4036

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## Abstract Bone morphogenetic proteins (BMPs) have been shown to regulate both osteoblasts and osteoclasts. We previously reported that BMP2 could directly enhance RANKL‐mediated osteoclast differentiation by increasing the size and number of osteoclasts. Similarly, genetic deletion of the BMP ant