## Abstract Mouse embryonic fibroblasts (MEFs) can be differentiated into fully functional chondrocytes in response to bone morphogenetic proteinβ2 (BMPβ2). The expression of Sox9, a critical transcription factor for the multiple steps of chondrogenesis, has been reported to be upregulated during t
β¦ LIBER β¦
Bone Morphogenetic Protein-2 induces chromatin remodeling and modification at the proximal promoter of Sox9 gene
β Scribed by Qiuhui Pan; Yanfeng Wu; Tianxin Lin; Herui Yao; Zhonghan Yang; Guoquan Gao; Erwei Song; Huiyong Shen
- Book ID
- 116297921
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 499 KB
- Volume
- 379
- Category
- Article
- ISSN
- 0006-291X
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## Abstract Insulinβlike growth factorβI (IGFβI) promotes bone formation by stimulating proliferation and differentiation of osteoblasts. Bone sialoprotein (BSP), is thought to function in the initial mineralization of bone, is selectively expressed by differentiated osteoblast. To determine the mo