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Bone metastasis is strongly associated with estrogen receptor–positive/progesterone receptor–negative breast carcinomas

✍ Scribed by Bing Wei; Jianmin Wang; Patricia Bourne; Qi Yang; David Hicks; Hong Bu; Ping Tang

Book ID: 116534560
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 580 KB
Volume: 39
Category: Article
ISSN: 1532-8392
DOI: 10.1016/j.humpath.2008.05.010

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## Abstract Mutations in DNA double‐strand breaks (DSB) repair genes are involved in the pathogenesis of hereditary mammary tumors, it is, however, still unclear whether defects in this pathway may play a role in sporadic breast cancer. In this study, we initially determined mRNA expression of 15 D