Bone marrow necrosis has been regarded as an indicator of very poor prognosis in malignant disease. The cause and incidence are unknown, and reports of treatment response are few. We describe four children with marrow necrosis at presentation with acute lymphocytic leukemia (ALL), all of whom entere
✦ LIBER ✦
Bone marrow karyotypes in 94 children with acute leukemia
✍ Scribed by S. Heim; A. N. Békàssy; S. Garwicz; J. Heldrup; U. Kristoffersson; N. Mandahl; T. Wiebe; F. Mitelman
- Book ID
- 114791273
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 544 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0902-4441
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## Abstract In a retrospective review which covered the whole Dutch childhood population of approximately 3 million children we studied the prognosis in 164 children with acute lymphoblastic leukemia (ALL) who were initially treated between 1973 and 1983, and who had an isolated bone marrow relapse