✦ LIBER ✦

Bone marrow histopathologic patterns and immunologic findings in B-chronic lymphocytic leukemia

✍ Scribed by Emilio Montserrat; Joao Pedro Marques-Pereira; M. Teresa Gallart; Ciril Rozman

Publisher: John Wiley and Sons
Year: 1984
Tongue: English
Weight: 443 KB
Volume: 54
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19840801)54:3<447::aid-cncr2820540312>3.0.co;2-z

No coin nor oath required. For personal study only.

✦ Synopsis

In 82 patients with B-chronic lymphocytic leukemia, the correlations between the histopathologic bone marrow patterns (interstitial, nodular, mixed, and diffuse), serum immunoglobulin (Ig), and blood B-lymphocyte levels and T-lymphocyte levels have been analyzed. The most commonly lowered Ig class was 1gM (43% of cases) followed by IgA (35%), and IgC (10%). There was a trend to a more frequent decrease of Ig levels when "advanced" bone marrow patterns (mixed + diffuse) were compared with the earlier ones (interstitial + nodular). The frequency of such a decrease was statistically significant for IgA class (P c 0.01). The absolute number of blood T-lymphocytes was increased in the diffuse pattern Cancer 54A47-451, 1984.

(P < 0.01).

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