Upregulation of matrix metalloproteinase
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Els Van Valckenborgh; Marleen Bakkus; Carine Munaut; Agnes NoΓ«l; Yves St. Pierre
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Article
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2002
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John Wiley and Sons
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French
β 453 KB
## Abstract MM is a Bβcell malignancy mainly characterized by monoclonal expansion of plasma cells in the BM, presence of paraprotein in serum and occurrence of osteolytic bone lesions. MMPs are a family of proteolytic enzymes that can contribute to cancer growth, invasion, angiogenesis, bone degra