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Bone marrow cells inhibit the generation of autologous EBV-specific CTL

✍ Scribed by Yide Jin; Laphalle Fuller; Violet Esquenazi; Bonnie B Blomberg; Anne Rosen; Andreas G Tzakis; Camillo Ricordi; Joshua Miller

Book ID
117414508
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
541 KB
Volume
61
Category
Article
ISSN
0198-8859

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EBV-associated lymphoproliferative disorders (EBV-LPD) are a significant problem after hemopoietic stem cell transplantation from unrelated donors or mismatched family members. Risk factors include T-cell depletion, MHC mismatch, and intensity of immunosuppression. New therapeutic strategies involve