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Bone marrow cell gene expression profiles characterize several mechanisms of action of hydroxyurea in sickle cell anemia

✍ Scribed by Flávia C. Costa; Anderson F. Cunha; Andre Fattori; Tarcisio S. Peres; Gustavo G.L. Costa; Tiago F. Machado; Dulcineia M. de Alburquerque; Sheley Gambero; Carolina Lanaro; Sara T.O. Saad; Fernando F. Costa

Book ID: 116304224
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 62 KB
Volume: 38
Category: Article
ISSN: 1079-9796
DOI: 10.1016/j.bcmd.2006.10.033

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## Abstract The red bone marrow (BM) is an important indicator organ of hematogenous micrometastatic spread of carcinomas. Characterization of biological properties specific for BM micrometastatic cells, however, is technically challenging due to the limited number of target cells usually available