Five years of adjuvant therapy with tamoxifen was considered the gold-standard treatment for postmenopausal women with estrogen receptor-positive breast cancer for many years. Data from a core group of clinical trials investigating the safety and efficacy of aromatase inhibitors (AIs) have challenge
Bone health issues in women with early-stage breast cancer receiving aromatase inhibitors
β Scribed by Adam M. Brufsky
- Book ID
- 107546570
- Publisher
- Current Science Inc.
- Year
- 2008
- Tongue
- English
- Weight
- 270 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1523-3790
No coin nor oath required. For personal study only.
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## Abstract ## BACKGROUND. Letrozole is safe and effective in postmenopausal women with estrogen receptorβpositive early breast cancer, but longβterm aromatase inhibitor use may cause bone loss and increase fracture risk. This study evaluated an immediate or delayed strategy of bone protection the