Bone calcium turnover, formation, and resorption in bromocriptine- and prolactin-treated lactating rats
β Scribed by Sutada Lotinun; Liangchai Limlomwongse; Vorachai Sirikulchayanonta; Nateetip Krishnamra
- Book ID
- 111637852
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 141 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0969-711X
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## Abstract The effect of the bisphosphonate dichloromethylene biphosphonate (Cl~2~MBP) on orthotopic and heterotopic bone, induced by implants of demineralized bone matrix (DBM) in rats was analyzed, with special reference to bone resorption. The heterotopic bone was formed by induction for 3 week
Male ACI rats were treated with estradiol to induce hyperprolactinemia and pituitary hypertrophy and hyperplasia. Animals received estradiol alone or with tamoxifen or bromocriptine for 4, 8, or 12 weeks. Estradiol treatment resulted in time-dependent increases in pituitary wet weight and serum prol