Bone-Bio Material Interface

✍ Scribed by J.E. Davies

• Publisher: University of Toronto Press
• Year: 1991
• Tongue: English
• Leaves: 516
• Category: Library

✦ Synopsis

Topics of the papers include current understanding of the influence of materials surfaces on bone generation; bone cell response to materials; molecular biological probes to study the interface; mechanical influence on interfacial biology; and retrieval analysis for interpreting interfacial phenomena.

✦ Table of Contents

Contents
Foreword
Preface
Acknowledgments
Part 1: The Material Surface
1. Surface Characterization of Implant Materials: Biological Implications
2. The Biomaterial-Tissue Interface and Its Analogues in Surface Science and Technology
3. Surface Reaction Kinetics and Adsorption of Biological Moieties: A Mechanistic Approach to Tissue Attachment
4. Titanium and Its Oxide Film: A Substrate for Formation of Apatite
5. Titanium: Immersion-Induced Surface Chemistry Changes and the Relationship to Passive Dissolution and Bioactivity
6. Kinetics of Mineralization, Demineralization, and Transformation of Calcium Phosphates at Mineral and Protein Surfaces
7. Substrate Surface Dissolution and Interfacial Biological Mineralization
8. High-Resolution Electron Microscopy of a Bone Implant Interface
Part 2: Bone Proteins and Other Macromolecules
9. Non-Collagenous Bone Proteins and Their Role in Substrate-Induced Bioactivity
10. Role of Adhesive Proteins and Integrins in Bone and Ligament Cell Behavior at the Material Surface
11. Non-Endocrine Regulation of Bone Cell Activity
12. Osteogenesis Induced by BMP-Coated Biomaterials: Biochemical Principles of Bone Reconstruction in Dentistry
13. Ceramic Synthesis using Biological Processes
Parts 1 and 2 - General Discussion
Part 3: Cellular Activity at the Interface
14. Inflammatory Cell Response to Bone Implant Surfaces
15. Modulation of Cell Activity by Titanium Peroxy Compounds
16. Behaviour of Osteoblasts on Micromachined Surfaces
17. Osteoblast Reactions to Charged Polymers
18. Cell-Mediated Bone Regeneration
19. The Influence of Sputtered Bone Substitutes on Cell Growth and Phenotypic Expression
20. Early Extracellular Matrix Synthesis by Bone Cells
21. Transmission Electron Microscopical Identification of Extracellular Matrix Components using Immunocytochemistry
22. Molecular Biological Approaches to Investigate Cell/Biomaterial Interactions
23. Biological Cascades of Fracture Healing as Models for Bone-Biomaterial Interfacial Reactions
24. Tissue Responses to Bone-Derived and Synthetic Materials
25. Hard and Soft Connective Tissue Growth and Repair in Response to Charged Surfaces
26. Deposition of Cement-like Matrix on Implant Materials
27. Polymer Reactions Resulting in Bone Bonding: A Review of the Biocompatibility of Polyactive
28. Comparative Morphology of the Bone Interface with Glass Ceramics, Hydroxyapatite, and Natural Coral
29. Interfacial Reactions to Bioactive and Non-bioactive Bone Cements
30. Modulation of Bone Ingrowth by Surface Chemistry and Roughness
31. Comparative Push-out Data of Bioactive and Non-bioactive Materials of Similar Rugosity
32. Quantified Bone Tissue Reactions to Various Metallic Materials with Reference to the So-called Osseointegration Concept
Part 5: Mechanical Effects on Interfacial Biology
33. Effect of Mechanical Stress on Tissue Differentiation in the Bony Implant Bed
34. Quantitative Evaluation of the Effect of Movement at a Porous Coated Implant-Bone Interface
35. Bone Ingrowth into Porous Coatings Attached to Prostheses of Differing Stiffness
36. Influence of Biomechanical Factors at the Bone-Biomaterial Interface
37. Bone Bonding Behavior of Biomaterials with Different Surface Characteristics under Load-Bearing Conditions
Part 5 - General Discussion: The Effect of Micromotion on Bone Healing
Part 6: Retrieval Analysis for Interpreting Interfacial Phenomena
38. Bone-Biomaterial Interfaces of Retrieved Implants
39. Ultrastructural Investigation and Analysis of the Interface of Retrieved Metal Implants
40. Synovial Cells at the Interface with Retrieved Implants
41. Phenotypic Characteristics of Inflammatory Cells Derived from Hip Revision Capsules
42. Bone Bonding to Retrieved Hydroxyapatite- Coated Human Hip Prostheses
Part 6 - General Discussion
Part 7: The Industrial Perception
Biographical Sketches of Invited Attendees at the Bone-Biomaterial Interface Workshop, Toronto, December 3 and 4, 1990
Affiliations of Contributing Authors
Index