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Bolus Versus Continuous High-Dose Omeprazole Infusion Combined with Endoscopic Hemostasis in Peptic Ulcer Bleeding. A Randomized, Multicenter, Italian Study

✍ Scribed by Angelo Andriulli; Silvano Loperfido; Rosaria Focareta; Pietro Leo; Fabio Fornari; Alessandro Caroli; Antonio Merla; Paolo Tonti; Gianni Imperiale; Antonio Spadaccini; Sergio Peyre; Riccardo Marmo; Antonella Garripoli; Giovanni Forte; Francesco Perri

Book ID: 119244113
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 46 KB
Volume: 65
Category: Article
ISSN: 1097-6779
DOI: 10.1016/j.gie.2007.03.115

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## Abstract ## Background Rebleeding from peptic ulcers is a major contributor to death. This study compared standard (40-mg intravenous infusion of omeprazole once daily for 3 days) and high-dose (80-mg bolus of omeprazole followed by 8-mg/h infusion for 72 h) in reducing the rebleeding rate (pri