Body iron metabolism and pathophysiology of iron overload
β Scribed by Yutaka Kohgo; Katsuya Ikuta; Takaaki Ohtake; Yoshihiro Torimoto; Junji Kato
- Book ID
- 107618571
- Publisher
- Carden Jennings Publishing
- Year
- 2008
- Tongue
- English
- Weight
- 287 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0925-5710
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Iron is indispensible for life, essential for such processes as oxygen transport, electron transfer, and DNA synthesis. Because of iron's virtual insolubility and potential toxicity, specialized mechanism and molecules for its acquisition, transport, and storage in a soluble, nontoxic form have evol
Hereditary hemochromatosis, a very common genetic defect in the Caucasian population, is characterized by progressive tissue iron overload which leads to irreversible organ damage if it is not treated timely. The elucidation of the molecular pathways of iron transport through cells and its control h