Body Composition in Homozygous β-Thalassemia
✍ Scribed by J. KALEF-EZRA; A. ZIBIS; N. CHALIASSOS; I. HATZIKONSTANTINOU; A. KARANTANAS
- Book ID
- 111396450
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 155 KB
- Volume
- 904
- Category
- Article
- ISSN
- 0890-6564
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Homozygous beta-thalassemia intermediate (TI) differs from thalassemia major (TM) in being less severe clinically. Associated alpha-thalassemia could account for the TI phenotype by reducing the alpha/non-alpha chain imbalance. We have analyzed the alpha loci of 9 TI and 11 TM patients by restrictio
Different degrees of severity of anemia are presented in three siblings with homozygous beta-thalassemia. II-1, the most severely affected one, is splenectomized and needs frequent blood transfusion, while II-4 has mild anemia and never receives transfusion. II-3 has moderate anemia and mild jaundic