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BMP Type II Receptor Is Required for Gastrulation and Early Development of Mouse Embryos

โœ Scribed by Hideyuki Beppu; Masahiro Kawabata; Toshiaki Hamamoto; Anna Chytil; Osamu Minowa; Tetsuo Noda; Kohei Miyazono

Book ID
115598419
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
299 KB
Volume
221
Category
Article
ISSN
0012-1606

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BMP type I receptor ALK2 is essential fo
BMP type I receptor ALK2 is essential for proper patterning at late gastrulation during mouse embryogenesis
โœ Yoshihiro Komatsu; Gregory Scott; Andre Nagy; Vesa Kaartinen; Yuji Mishina ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 859 KB

## Abstract Bone morphogenetic proteins (BMPs) have multiple functions during vertebrate development. Previously, it was shown that BMP type I receptor ALK2 (also known as ACVRI, ActRI, or ActRIA) was important for normal mouse gastrulation by deleting exon 4 or exon 5 of __Alk2__. Recently, flanki