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BMP-2 regulates cardiomyocyte contractility in a phosphatidylinositol 3 kinase-dependent manner

✍ Scribed by Nandini Ghosh-Choudhury; Sherry L Abboud; Bysani Chandrasekar; Goutam Ghosh Choudhury

Book ID
117105454
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
108 KB
Volume
544
Category
Article
ISSN
0014-5793

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## Abstract Previously, we showed that laminin‐binding to the dystrophin glycoprotein complex (DGC) of skeletal muscle causes a heterotrimeric G‐protein (Gαβγ) to bind, changing the activation state of the Gsα subunit. Others have shown that laminin‐binding to the DGC also leads to Akt activation.