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BMP-2 mediates retinoid-induced apoptosis in medulloblastoma cells through a paracrine effect

✍ Scribed by Hallahan, Andrew R; Pritchard, Joel I; Chandraratna, Roshantha A S; Ellenbogen, Richard G; Geyer, J Russel; Overland, Ryan P; Strand, Andrew D; Tapscott, Stephen J; Olson, James M


Book ID
109933279
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
403 KB
Volume
9
Category
Article
ISSN
1078-8956

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## Abstract Degranulated mast cells are present in the subendothelial space of eroded (de‐endothelialized) coronary atheromas. Upon degranulation, mast cells secrete into the surrounding tissue an array of preformed and newly synthesized mediators, including proapoptotic molecules, such as chymase