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Blood levels of aspirin following the ingestion of commercial aspirin-containing tablets by humans

✍ Scribed by V. Cotty; F. Zurzola; T. Beezley; A. Rodgers


Publisher
John Wiley and Sons
Year
1965
Tongue
English
Weight
284 KB
Volume
54
Category
Article
ISSN
0022-3549

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## Abstract In vitro aspirin hydrolysis rates were measured in fresh human whole blood and in its separate components. The half‐life of aspirin in whole blood was relatively rapid (mean 22.2 Β± 3.9 minutes) and exhibited a significant negative correlation with hematocrit (r = βˆ’0.96). Hydrolysis of a