Blood hemolysis by PTFE and polyurethane vascular prostheses in anin vitro circuit
✍ Scribed by Martz, Hugues ;Paynter, Royston ;Losier, Michel ;Domurado, Dominique ;Forest, Jean-Claude ;Guidoin, Robert
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 550 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0021-9304
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✦ Synopsis
In order to improve understanding of the appearance of bright yellow stains in vivo (consecutive to the absorption of bilirubin) on a novel microporous, hydrophilic polyetherurethaneurea vascular prosthesis, the in vitro hemolytic activity of the material was compared with expanded polytetrafluoroethylene and silicone rubber. The results show that the tendency of the poly-etherurethaneurea to produce free hemoglobin is low, so that the yellow staining observed is likely to be a result of the contact between the polymer and thrombi: Bilirubin is produced because of hemoglobin degradation in the thrombi rather than an active hemolysis on the surface of the prosthesis itself.