Blood-group-like substances in some marine invertebrates. III. Glycoproteins with blood-group a specificity in the cephalopodsSepia officinalis L. andLoligo vulgaris Lam
✍ Scribed by Renwrantz, Lothar ;Uhlenbruck, Gerhard
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 494 KB
- Volume
- 188
- Category
- Article
- ISSN
- 0022-104X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Two cephalopods, Sepia officinalis L. and Loligo vulgaris Lam., have been investigated for soluble inhibitors of anti human blood‐group agglutinins. Only a weak inhibition was observed with respect to human anti‐A isoagglutinin. In the agar‐gel double diffusion test, however, the test substances showed a very strong precipitation reaction with heterophile anti‐A from snails. The precipitation lines were identical with that of A substance from peptone. The A‐like substances found were identified as glycoproteins containing terminal, non‐reducing bound α‐N‐acetyl‐D‐galactosamine. The biological importance of these macromolecules is discussed with particular reference to their reactive site.