Blood compatibility of methyl, methyl vinyl, methyl phenyl, and trifluoropropylmethylvinyl silicone rubber without silica fillers in the spiral-coiled membrane lung
✍ Scribed by Kolobow, T. ;Tomlinson, T. A. ;Pierce, J. E.
- Book ID
- 102873795
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- English
- Weight
- 513 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0021-9304
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✦ Synopsis
Abstract
Spiral‐coiled membrane lungs of 0.6 m^2^ surface area were fabricated from silicone rubber membranes coated with four types of commercially available pure‐gum polysiloxane rubber: 1) polytrifluoropropylmethylvinylsiloxane, 2) polymethylphenylsioxane, 3) polymethylvinylsiloxane, and 4) polydimethylsiloxane.
Membrane lungs were tested in an arteriovenous shunt without added heparin after bypass was begun. All groups except group 4 had major rise in resistance to blood flow or clotting in over 33% of the membrane lungs studied, after 6 hr of bypass. Membrane lungs with polydimethylsiloxane (group 4) had no rise in resistance to blood flow during 24 hr of bypass and had the least amount of changes in blood platelet count.