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Blood CD8+ T cell responses against myelin determinants in multiple sclerosis and healthy individuals

✍ Scribed by Laureline Berthelot; David-Axel Laplaud; Ségolène Pettré; Caroline Ballet; Laure Michel; Sophie Hillion; Cécile Braudeau; Francine Connan; Fabienne Lefrère; Sandrine Wiertlewski; Jean-Gérard Guillet; Sophie Brouard; Jeannine Choppin; Jean-Paul Soulillou

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
379 KB
Volume
38
Category
Article
ISSN
0014-2980

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T cell response to myelin basic protein
T cell response to myelin basic protein epitopes in multiple sclerosis patients and healthy subjects
✍ Roland Liblau; Elisabeth Tournier-Lasserve; Jacqueline Maciazek; Gérad Dumas; Od 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 388 KB

T cell lines and clones specific for human myelin basic protein (BP) were selected from three multiple sclerosis (MS) patients and two healthy subjects and tested for their proliferative responses to a battery of synthetic peptides, 9 to 21 amino acid residues long. The combined amino acid sequence