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Blood-Brain Barrier Transport of L-iyrosine Conjugates: a Model Study for the Brain Targeting using Large Neutral Amino Acid Transport System

โœ Scribed by Ohnishi, Toshimasa; Maruyama, Tetsu; Higashi, Sohei; Awazu, Shoji


Book ID
121866618
Publisher
Informa plc
Year
2000
Tongue
English
Weight
439 KB
Volume
8
Category
Article
ISSN
1061-186X

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The blood-brain barrier (BBB) is formed by the presence of tight junction complexes between brain endothelial cells that restrict paracellular permeability. As a consequence, a number of transport proteins are expressed on cerebral endothelial cells to facilitate the transport of nutrients into the