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Blood and cerebrospinal fluid pharmacokinetics of the novel anticonvulsant levetiracetam (ucb L059) in the rat

✍ Scribed by H.C Doheny; N Ratnaraj; M.A Whittington; J.G.R Jefferys; P.N Patsalos


Book ID
108460531
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
119 KB
Volume
34
Category
Article
ISSN
0920-1211

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Various parameters which may be useful in quantification of drug transit from blood into CSF and vice versa after a short duration infusion are compared here by recalculating previously published data from our group. Due to the slower entry into and elimination from the CSF compartment as compared t