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Blocking the P2X7 Receptor in a Rat Nerve-Injury Model Improves Long Term Functional Outcomes

✍ Scribed by Rodriguez-Feo, C.L.; Sexton, K.; Boyer, R.B.; Pollins, A.O.; Cardwell, N.L.; Nanney, L.B.; Shack, B.; Thayer, W.P.

Book ID: 122516807
Publisher: Elsevier Science
Year: 2013
Tongue: English
Weight: 187 KB
Volume: 179
Category: Article
ISSN: 0022-4804
DOI: 10.1016/j.jss.2012.10.377

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Background Continuous hyperglycemia is implicated in the pathogenesis of chronic diabetic complications. It is not well known, however, how and to what extent the development of neuropathy is inhibited by blood glucose control in subjects with Type 2 diabetes. We investigated therefore the effects o