Blocking of N-acetylglucosaminyltransferase V induces cellular endoplasmic reticulum stress in human hepatocarcinoma 7721 cells
✍ Scribed by Fang, Huan; Huang, Wei; Xu, Ying Ying; Shen, Zong Hou; Wu, Chao Qun; Qiao, Shou Yi; Xu, Yan; Yu, Long; Chen, Hui Li
- Book ID
- 110020714
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 917 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0007-0610
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## Abstract We previously demonstrated that endoplasmic reticulum (ER) stress was triggered in human hepatocarcinoma 7721 cells transfected with antisense cDNA of N‐acetylglucosaminyltransferase V (GnT‐V‐AS/7721) which were more susceptible to apoptosis induced by all‐trans retinoic acid (ATRA). In
## Abstract We previously reported that all‐__trans__‐retinoic acid (ATRA) induced apoptosis in __N__‐acetylglucosaminyltransferase V (GnT‐V) repressed human hepatocarcinoma 7721 (GnT‐V‐AS/7721) cells via endoplasmic reticulum (ER) stress. In addition to confirming these findings, we further found