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Blocking late cholesterol biosynthesis inhibits the growth of transplanted Morris hepatomas (7288CTC) in rats

✍ Scribed by G Xu; G Salen; M Lea; GS Tint; LB Nguyen; AK Batta; TS Chen; S Shefer

Book ID: 118686341
Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 238 KB
Volume: 24
Category: Article
ISSN: 0270-9139
DOI: 10.1053/jhep.1996.v24.pm0008690417

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Blocking late cholesterol biosynthesis inhibits the growth of transplanted Morris hepatomas (7288CTC) in rats

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cholesterol levels. Thus, inhibiting late cholesterol syn-The conversion of 7-dehydrocholesterol to cholesterol thesis hinders growth of rapidly enlarging malignant is the last reaction in the cholesterol biosynthesis pathtumors. (HEPATOLOGY 1996;24:440-445.) way catalyzed by the microsomal enzyme,

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