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Blockade of substantia nigra dopamine D1 receptors reduces intravenous cocaine reward in rats

✍ Scribed by Matthew G. Quinlan; Ruth Sharf; David Y. Lee; Roy A. Wise; Robert Ranaldi


Publisher
Springer
Year
2004
Tongue
English
Weight
333 KB
Volume
175
Category
Article
ISSN
0033-3158

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It has been proposed that dopamine and glutamate affect basal ganglia output, in part, through interactions between D1 receptors and NMDA receptors. The present study examined whether N-methyl-D-aspartate (NMDA) receptor antagonists affect the neurophysiological responses of substantia nigra pars co