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Blockade of GABA Uptake with Tiagabine Inhibits Audiogenic Seizures and Reduces Neuronal Firing in the Inferior Colliculus of the Genetically Epilepsy-Prone Rat

โœ Scribed by Carl L. Faingold; Marcus E. Randall; Cathy A.Boersma Anderson

Book ID
115606105
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
530 KB
Volume
126
Category
Article
ISSN
0014-4886

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โœ R.A. Browning; M.L. Lanker; C.L. Faingold ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 831 KB

Genetically epilepsy-prone rats (GEPRs) which display tonic seizures (GEPR-9s) in response to acoustic stimulation were used in these studies. Other laboratories have shown that CEPR-9s have a reduced concentration of brain norepinephrine (NE). Previous reports have also indicated that audiogenie se