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Blockade of cardiac sarcoplasmic reticulum K+ channel by Ca2+: two-binding-site model of blockade

โœ Scribed by Liu, Q.Y.; Strauss, H.C.

Book ID
119409595
Publisher
Biophysical Society
Year
1991
Tongue
English
Weight
459 KB
Volume
60
Category
Article
ISSN
0006-3495

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The purified ryanodine receptor channel of the sheep cardiac muscle sarcoplasmic reticulum (SR) membrane functions as a calcium-activated cation-selective channel under voltage-clamp conditions following reconstitution into planar phospholipid bilayers. We have investigated the effects of the tetra-