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Blockade of adenosine and dopamine receptors inhibits the development of rapid tolerance to ethanol in mice

✍ Scribed by Luciano C. Batista; Rui D. S. Prediger; Gina S. Morato; Reinaldo N. Takahashi


Publisher
Springer
Year
2005
Tongue
English
Weight
154 KB
Volume
181
Category
Article
ISSN
0033-3158

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We have developed a precise quantal method for assessing the sensitivity to ethanol in the mouse. Mice placed on a clamped stationary horizontal dowel are scored ataxic or not ataxic depending on whether they are able to remain on the dowel during a 30-s observation period. A threshold blood ethanol