Blockade and reversal of spinal morphine tolerance by peptide and non-peptide calcitonin gene-related peptide receptor antagonists
β Scribed by Kelly J Powell; Weiya Ma; Maaja Sutak; Henri Doods; Remi Quirion; Khem Jhamandas
- Book ID
- 110005333
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 321 KB
- Volume
- 131
- Category
- Article
- ISSN
- 0007-1188
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## Abstract The present study was undertaken to investigate the plasticity of calcitonin geneβrelated peptide (CGRP) in antinociception after morphine tolerance in rats. The hindpaw withdrawal latencies (HWLs) to both thermal and mechanical stimulation increased significantly after intracerebrovent