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Bleomycin-induced nuclear factor-κB activation in human bronchial epithelial cells involves the phosphorylation of glycogen synthase kinase 3β

✍ Scribed by Yan Ma; Manxiang Wang; Naping Li; Renliang Wu; Xi Wang


Book ID
119380846
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
774 KB
Volume
187
Category
Article
ISSN
0378-4274

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## Abstract Glycogen synthase kinase 3β (GSK3β) activity is regulated by phosphorylation processes and regulates in turn through phosphorylation several proteins, including eukaryotic initiation factor 2B (eIF2B). Serine 9 phosphorylation of GSK3β (pGSK3βSer9), usually promoted by activation of the