Bleomycin enhances the tyrosinase activity of human malignant melanoma cells in culture
✍ Scribed by August Bernd; Peter Altmeyer; Gisela Schäfer; Wolfgang Ch. Marsch; Hans Holzmann
- Book ID
- 113199544
- Publisher
- Elsevier Science
- Year
- 1986
- Weight
- 193 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0031-6989
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## Abstract Serum tyrosinase activity has been measured by adapting the [^3^]tyrosine assay for tyrosinase and significant elevations of serum tyrosinase activity were found in patients with malignant melanoma. In contrast to findings in a study which utilized [^14^C]tyrosine, augmented levels of t
## Abstract The tyrosinase (EC 1.14.18.1) activity of cultured mouse melanoma cells B16 in the stationary phase of growth, depends greatly on the pH of the medium and the kind of sugar present. The enzyme activity of a homogenate of cells grown at pH 7.2 in Eagles's MEM supplemented with 10% new b