𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Bleeding time in Uremia: A useful test to assess clinical bleeding

✍ Scribed by Dr. R. W. Steiner; Cecil Coggins; Dr. Angelina C. A. Carvalho

Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
615 KB
Volume
7
Category
Article
ISSN
0361-8609

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Modified Ivy bleeding time (template) and platelet aggregation to ADP, epinephrine, and collagen were studied in 26 uremic patients who had not recently ingested anti‐platelet drugs. Regardless of the aggregating agent used, the abnormalities in platelet aggregation were often mild, even with advanced uremia, and frequently less severe than the effects of common anti‐platelet drugs. The inhibition of collagen‐induced aggregation was significantly correlated with both increased bleeding time and blood urea nitrogen. Platelet aggregation was not discriminative between clinically bleeding and non‐bleeding groups of patients, but the bleeding time was helpful in this regard. In certain cases, the aggregometric patterns differed between drug‐induced and uremic thrombocytopathies. Platelet aggregometry appears to be of little help clinically in assessing the severity of the uremic bleeding diathesis.

📜 SIMILAR VOLUMES

Background, rationale, and design of a c
Background, rationale, and design of a clinical trial to assess the effects of platelet dose on bleeding risk in thrombocytopenic patients
✍ Sherrill J. Slichter 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 117 KB 👁 1 views

## Abstract Outlined is the background and rationale for the initiation of a randomized prospective platelet transfusion trial to evaluate the effects of platelet dose on hemostasis and platelet utilization rates. This clinical trial is being performed by the newly established Transfusion Medicine/

Tonsillectomy in children: A five-factor
Tonsillectomy in children: A five-factor analysis among three techniques—Reporting upon clinical results, anesthesia time, surgery time, bleeding, and cost
✍ Riccardo D'Eredità 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB

## Abstract ## Objectives: Improved technology claims better clinical results for adenotonsillectomy (T&A) in children, and promoters of each technique announce many virtues over one another, year after year. However, cost remains one variable that is not always thoroughly addressed. In this study

The bleeding risk index : A clinical pre
The bleeding risk index : A clinical prediction rule to guide the prophylactic use of platelet transfusions in patients with lymphoma or solid tumors
✍ Linda S. Elting; Charles G. Martin; Danna J. Kurtin; Scott B. Cantor; Edward B. 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 133 KB 👁 1 views

## Abstract ## BACKGROUND The correlation between platelet count and bleeding has been well described, although no formal methods for applying this information to clinical decisions are available. The authors developed a clinical prediction rule to guide the prophylactic use of platelet transfusio