✦ LIBER ✦
Blastogenesis dominant 1: A sequence with midline anomalies and heterotaxy
✍ Scribed by de Meeus, Anne; Sarda, Pierre; Tenconi, Romano; Ferrière, Marc; Bouvagnet, Patrice
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 138 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0148-7299
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✦ Synopsis
Lateralization defect is a heterogeneous condition with different modes of transmission (autosomal recessive, dominant or X-linked).
Here, we report on 3 additional families that contribute to the description of phenotypic anomalies of the autosomal dominant type. Phenotypic anomalies include: lateralization defects, cardiac malformations, diaphragmatic hernia, urologic and neurologic anomalies. We suggest calling this sequence BGD1 for blastogenesis dominant 1 because the deleterious effect probably occurs during blastogenesis and involves not only lateralization but other defects as well. Am.