𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Bladder cancer and occupational exposure to polycyclic aromatic hydrocarbons

✍ Scribed by Stcfano Bonassi; Franco Mfrlo; Neil Pearce; Riccardo Puntoni

Publisher
John Wiley and Sons
Year
1989
Tongue
French
Weight
498 KB
Volume
44
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

The association between occupational exposure to polycyclic aromatic hydrocarbons (PAH) and bladder cancer development was investigated in a population-based case-control study carried out in the Bormida valley, Italy. One hundred and twenty-one male cases and 342 male controls, matched by age, were collected from local hospitals. Occupational exposure to PAH and aromatic amines (AA) was evaluated by means of a job exposure matrix, constructed specifically for this study. Subjects considered as sharing a "definite exposure to PAH" showed an increased risk even after adjustment for cigarette smoking and exposure to AA (OR = 2.14, 95% CL 0.82-5.60). No elevation in risk was found for the category "possible exposure to PAH" (OR = I .05, 95% CL 0.45-2.44).

The findings of this study are consistent with previous studies indicating PAH as a risk factor for bladder cancer. A possible residual confounding effect due to AA impurities is discussed.

πŸ“œ SIMILAR VOLUMES

Occupation, exposure to polycyclic aroma
Occupation, exposure to polycyclic aromatic hydrocarbons and laryngeal cancer risk
✍ Heiko Becher; Heribert Ramroth; Wolfgang Ahrens; Angela Risch; Peter Schmezer; A πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 French βš– 113 KB

## Abstract Primary risk factors for laryngeal cancer are smoking and alcohol. The relevance of occupational exposures in the etiology of laryngeal cancer is not yet clarified. Some studies have suggested various occupational agents as additional causal risk factors. A population‐based case–control

Relationship between blood antioxidants
Relationship between blood antioxidants and occupational exposure to polycyclic aromatic hydrocarbons in coke oven workers
✍ Rachel Nadif; Labico Diallo; Lucienne Mayer; Martine Dusch; Jean-Marc Porcher; P πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 99 KB πŸ‘ 1 views

## Background: We investigated if blood cu++/zn++ superoxide dismutase, glutathione peroxidase, and catalase activities are increased and total plasma antioxidant concentration is decreased in coke oven workers exposed to polycyclic aromatic hydrocarbons. ## Methods: Ninety-six coke oven workers

Occupational exposure to dyes, metals, p
Occupational exposure to dyes, metals, polycyclic aromatic hydrocarbons and other agents and K-ras activation in human exocrine pancreatic cancer
✍ Juan Alguacil; Miquel Porta; Timo Kauppinen; NΓΊria Malats; Manolis Kogevinas; Al πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 French βš– 98 KB

ras genes are known critical DNA targets for chemical carcinogens. Exocrine pancreatic cancer (EPC) is the human tumor with the highest prevalence of K-ras mutations at diagnosis. We analyzed the relationship between past occupational exposure to dyes, metals, polycyclic aromatic hydrocarbons (PAHs)

Occupational exposure to chlorinated ali
Occupational exposure to chlorinated aliphatic hydrocarbons: Job exposure matrix
✍ M. R. Gomez; P. Cocco; M. Dosemeci; P. A. Stewart πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 870 KB

A job exposure matrix combining features to increase the accuracy of exposure assessment was developed to evaluate cancer risks from workplace exposures to six chlorinated aliphatic hydrocarbons (CAHs). A detailed description of the matrix is provided to satisfy the need for more in-depth discussion