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BlaB, a protein involved in the regulation ofStreptomyces cacaoiβ-lactamases, is a penicillin-binding protein

✍ Scribed by C. Raskin; C. Gérard; S. Donfut; F. Giannotta; G. Van Driessche; J. Van Beeumen; J. Dusart


Book ID
105757595
Publisher
Springer
Year
2003
Tongue
English
Weight
307 KB
Volume
60
Category
Article
ISSN
1420-682X

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A library of mutants of the RTEM 13-1actamase displayed on phage was created; it contained penicillin binding proteins (PBPs) as well as a small fraction of active B-lactamases. The library was submitted to a selection process to extract the B-lactamases i.e. the enzymes that turnover efficiently. T