Bivalent opioid peptides synthesized from μ selective monomers display preferential selectivity for δ receptors

Effects of intracerebroventricular injec

Effects of intracerebroventricular injection of opioid peptides selective for μ, δ and κ receptors on discriminative stimulus properties of pentazocine in the rat

✍ Makoto Ukai; Eiji Mori; Tsutomu Kameyama 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 131 KB 👁 1 views

The present study was designed to investigate the eects of centrally administered morphine and opioid peptides on the discriminative stimulus properties of pentazocine in the rat. Rats were trained to discriminate 3 mg/kg (s.c.) of pentazocine from vehicle in a shock avoidance paradigm. A 3 mg/kg (s