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Bisulfite and hydroxylamine mutagenesis: structures of sodium N 4-hydroxy-5,6-dihydrocytosine-6-sulfonate monohydrate and sodium N 4-hydroxy-1-methyl-5,6-dihydrocytosine-6-sulfonate tetrahydrate

✍ Scribed by Barnes, C. L. ;Hawkinson, S. W.


Book ID
114528624
Publisher
International Union of Crystallography
Year
1982
Weight
530 KB
Volume
38
Category
Article
ISSN
0567-7408

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## Abstract The syntheses of the deuterium‐labeled food mutagen 2‐amino‐1‐methyl‐6‐phenyl‐1H‐imidazo[4,5‐b]pyridine (PhIP) and its __N__‐hydroxy metabolite are described. Unlabeled PhIP is deuterated using a boron trifluoride phosphoric acid complex in one step. Labeled PhIP–^2^H~5~ is nitrosated t