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Bisphosphonate treatment in the oim mouse model alters bone modeling during growth

✍ Scribed by S.H. Rao; K.D. Evans; A.M. Oberbauer; R.B. Martin

Book ID
108159622
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
194 KB
Volume
41
Category
Article
ISSN
0021-9290

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## Abstract The current study addresses whether alterations in osteoclasts (OCs) derived from __oim/oim__ mice, an established model of moderate‐to‐severe OI, are present. Bone marrow cells from __oim/oim__ and wildtype (+/+) mice were cultured on bone slices in the presence of MCSF and RANKL and e