Bisphenol-A exposure during the period of blastocyst implantation alters uterine morphology and perturbs measures of estrogen and progesterone receptor expression in mice

Accelerated onset of uterine tumors in t

Accelerated onset of uterine tumors in transgenic mice with aberrant expression of the estrogen receptor after neonatal exposure to diethylstilbestrol

✍ John F. Couse; Vicki L. Davis; Rita B. Hanson; Wendy N. Jefferson; John A. McLac 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 293 KB 👁 1 views

The role of estrogen and the estrogen receptor (ER) in the induction and promotion of tumors was investigated by using transgenic MT-mER mice, which overexpress the ER. It was hypothesized that because of this abnormal expression of the ER, the reproductive-tract tissues of the MT-mER mice may be mo