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Bispecific monoclonal antibodies directed to CD16 and to a tumor-associated antigen induce target-cell lysis by resting NK cells and by a subset of NK clones

โœ Scribed by Silvano Ferrini; Ignazia Prigione; Silvia Miotti; Ermanno Ciccone; Claudia Cantoni; Qi Chen; Maria Ines Colnaghi; Lorenzo Moretta

Publisher
John Wiley and Sons
Year
1991
Tongue
French
Weight
716 KB
Volume
48
Category
Article
ISSN
0020-7136

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โœ Andreas Hombach; Wolfram Jung; Christoph Pohl; Christoph Renner; Ugur Sahin; Rud ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 808 KB

In order to target NK cells against the Hodgkin's-derived cell line L540, we developed bispecific monoclonal antibodies (Bi-MAbs) by somatic hybridization of the 2 mouse hybridoma cell lines HRS-3 and A9 which produce monoclonal antibodies (MAbs) with reactivity against the Hodgkin and Reed-Sternber